Results  Study selection

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Volume 1 Issue 1
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January 2024 
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ORIENTAL JOURNAL OF MEDICINE AND NATURAL SCIENCES 
“Innovative World” Scientific Research Support Center www.inno-world.uz
The initial search yielded 1195 citations. After accounting for duplicates, 790 
unique citations remained. Upon reviewing titles and abstracts, 772 studies were 
excluded as they did not meet the specified criteria. The full text of the remaining 
18 citations underwent a more detailed examination, revealing that 13 studies 
did not align with the inclusion criteria. Consequently, five studies that met the 
criteria were included in the systematic review. Further exploration of the 
references in relevant papers and citation searches did not yield additional 
studies meeting the inclusion criteria. Additionally, no unpublished relevant 
studies were obtained. 
 Study characteristics 
Characteristics of the included studies have been summarized in Table 
1
. 
Given the absence of comparable therapies reported in the included literature, 
a narrative review was conducted. 

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Volume 1 Issue 1
 | 
January 2024 
|
 
ORIENTAL JOURNAL OF MEDICINE AND NATURAL SCIENCES 
“Innovative World” Scientific Research Support Center www.inno-world.uz
All the studies included in the review focused on patients experiencing the 
initial clinical presentation of herpetic gingivostomatitis. Among these, three 
studies (1, 2, and 3) specifically targeted pediatric subjects aged 8 months to 12 
years, while the remaining two studies (4 and 5) included adolescents aged 12 to 
18 years. 
Notably, all the studies were conducted in hospital or university hospital 
settings, spanning across five different countries. 

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