• Compatibility Fluids: Glucose 5%. Y site: Zidovudine. Incompatibility
  • Neonatal Intensive Care Drug Manual




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    Adverse reactions

    Electrolyte derangements: Hypokalaemia, hypomagnesaemia, hyperkalaemia, hypocalcaemia.

    Renal: Elevated urea and creatinine, nephrogenic diabetes insipidus.

    Haematological: Anaemia, leucopenia, thrombocytopenia.

    Thrombophlebitis at the injection site.

    Gastrointestinal: Diarrhoea, vomiting, elevated liver enzymes.

    Infusion-related reactions: Fever, hypotension (rare in neonates).

    Skin rashes.

    Tachyarrhythmias, hypotension, hypertension and respiratory distress have been reported in adults.



    Compatibility

    Fluids: Glucose 5%.
    Y site: Zidovudine.

    Incompatibility

    Fluids: Sodium chloride 0.9%, Amino acid/glucose solution, lipid emulsion.
    Y Site: Not compatible with any medications commonly used in newborns. Do not mix with any medications.

    Stability

    Reconstituted and diluted solution stable for up to 24 hours at 2–8 °C.

    Storage

    Vial: Store below 25 °C. Do not freeze.

    Reconstituted solution: Stable for 24 hours at 2–8°C. Discard unused portion after 24 hours. Do not use the reconstituted solution or infusion if cloudy or a precipitate is present. Protect from light.



    Excipients

    No information


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    Neonatal Intensive Care Drug Manual

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