• Acute severe hypertension
  • Neonatal Intensive Care Drug Manual




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    Dosage/Interval

    Sedation:

    IV infusion: Loading dose of 0.5 to 1 microgram/kg over 15 minutes followed by a continuous infusion of 0.2 microgram/kg/hour and titrate up to a maximum of 1 microgram/kg/hour in hemodynamically stable neonates. [2]


    ORAL: 1 microgram/kg/dose 8 hourly and titrate it up to a maximum 2 micrograms/kg/dose 6 hourly. [2, 3] [Group consensus]
    Acute severe hypertension:

    10 microgram/kg infused over 4 hours. Additional dose of 5 microgram/kg may be given. [4] Consider continuous intra-arterial monitoring.



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    Neonatal Intensive Care Drug Manual

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